Metallomics is a multidisciplinary science that merges the fields of chemistry, biology, physics, and medicine to study the biological roles of metals and their impacts on human health.

Metallome is a fundamental concept in the field of metallomics, which represents the function of metal and metalloid species within a molecule, cell, tissue, organ, or organism.

Stable isotopes of metallome elements play an integral and critical role in human biology and have become an important area of study in the field of isotopic metallomics.

Isotopic signatures are instrumental for understanding the etiology of diseases and for developing the innovative therapies to repair cellular homeostasis.

Research shows that healthy cells/tissues are enriched in light isotopes, whose ratios shift toward a greater prevalence of heavy isotopes as people develop diseases.