We investigate the isotopic effects on metalloproteins, organelles, cells, and human physiology. With focus on stable isotopes of essential elements, we believe that isotopic signatures are instrumental for deciphering the etiology of many diseases and designing the mechanisms leading to restoring healthy cellular functions.
We are making the biotech history
We research the roles, fractions, and interactions of stable isotopes in human physiology to decipher the etiology of diseases and design the mechanisms leading to repairing healthy cellular functions and the metallome homeostasis.
We are changing the world
Empowered by our proprietary ISM platform and AI concepts, we spin-off biotech companies and set them to help people live better for longer by creating inherently-safe and clinically-effective drugs to slow-down and ultimately eradicate devastating diseases.
Precision Drug Delivery
The medical use of stable isotopes in various small molecules is pivotal for their ability to cross the blood-brain barrier, enabling direct engagement with metalloproteins and cellular processes. The inherent safety profile of stable isotopes in metallome highlights its transformative potential in the development of novel pharmaceuticals, hence, promising new era of treatments that are both more effective and clinically safe.
Utilizing sophisticated mass spectrometry techniques, we investigate the isotopic concentrations, distributions, and interactions of essential metals in protein folding, DNA repair, mitochondrial function, apoptosis, and other biological processes. Disruption of these functions are often linked to harmful protein aggregation, chronic inflammation and oxidative stress, and cellular death.
Understanding the isotopic effects in these processes will help to elucidate the basic mechanisms underlying vital life processes and to design inherently-safe and effective therapies capable to restore vital cellular and organ functions.
Our goal is to become the world's leading metallomics pharma company developing inherently safe, effective, and clinically de-risked, disease modifying drugs for treatment of complex diseases.